From: S.J. Van Sickle (sjvan@csd.uwm.edu)
Date: Tue Jul 08 2003 - 00:07:26 MDT
On Mon, 2003-07-07 at 18:27, Eliezer S. Yudkowsky wrote:
>>If dendrites and axons retract into the cell body within half an hour
> >>after the neuron has been starved of oxygen (!!!),
> >
> > ### This is not true.
>
> Maybe I've got it wrong. What's the correct time?
Well, as an extreme example:
apparently undamaged axons were detected immunohistochemically out to 168
hours (7 days) at room temperature. Whether these are enough undamaged
axons, whether the damaged axons retained sufficient clues to their
original structure, and whether other necessary structures remain
inferrable for reconstruction of a person are open questions.
This is likely near the upper limit. I have seen reports of more complete
survival of 6 to 24 hours. After about 18 hours the capillary bed and
blood brain barrier break down sufficiently that it becomes difficult to
impossible to perfuse cryoprotectants effectively, at which point the
bucket method starts looking not so bad.
steve van sickle
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