From: Rafal Smigrodzki (rafal@smigrodzki.org)
Date: Wed Feb 19 2003 - 09:38:12 MST
gts wrote:
> Rafal wrote:
>>>> ### I explained before but can do it again: selegiline did not slow
>>>> the progression of symptoms, merely symptomatically delayed the
>>>> time to levodopa, as shown by the loss of efficacy during washout.
>>>
>>> I stand by my words. Selegiline delayed the time to which symptoms
>>> become severe enough to require treatment with levodopa. That is
>>> "slowing the progression of Parkinson's disease symptoms" by
>>> anyone's definition, Rafal.
>>
>> ### No it isn't. The symptoms appeared at the same rate, but were
>> delayed.
>
> Uhh, excuse me but a delay in the appearance of parkinson's symptoms
> is the same thing as "slowing the progression of symptoms."
### You might want to peruse some literature on neurodegenerative disorders
before making this statement. In the medical community the terms "slowing
progression of disease", "slowing the progression of symptoms", and
"delaying the symptoms", have distinct meanings. You can see the newest
issue of "Neurology", with the review article on "Slowing Parkinson's
disease progression: recent dopamine agonist trials"
Neurology. 2003 Feb 11;60(3):381-9.
Rafal
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