Printing tissue

From: Alejandro Dubrovsky (s328940@student.uq.edu.au)
Date: Wed Jan 22 2003 - 21:13:15 MST


(
http://news.yahoo.com/news?tmpl=story2&cid=571&ncid=751&e=1&u=/nm/20030122/hl_nm/living_tissue_dc
)

Living Tissue to Be Hot Off the Printer

LONDON (Reuters) - Scientists are turning to desktop printers in an
effort to produce three-dimensional tubes of living tissue and possibly
even entire organs.

Instead of using a degradable scaffold and covering it with cells to
produce tissue, scientists in the United States are modifying ink jet
printers and using cells to create 3D structures.

"The work is a first step toward printing complex tissues or even entire
organs," New Scientist magazine said on Wednesday.

Although producing organs is a very long way away, many laboratories are
printing arrays of DNA, proteins and even cells.

Vladimir Mironov of the Medical University of South Carolina and Thomas
Boland of Clemson University in the same state have used a non-toxic,
biodegradable gel and animal cells to make the structures.

"By printing alternate layers of the gel and clumps of cells on to glass
slides, they have shown 3D structures such as tubes can be built,"
according to the magazine.

If the layers are thin enough the cells fuse when they come in contact
with each other and bits of tissue are formed. When the structure is
finished the gel can be removed.

"Like printing with different colors, placing different types of cells
in the ink cartridges should make it possible to recreate complex
structures consisting of multiple cells," the magazine explained.

But before scientists can produce organs they will have to solve the
problem of creating circulatory networks to provide oxygen and nutrients
to the cells in the structures.

But the scientists hope it will be possible.

"This could have the same kind of impact that Gutenberg's press did,"
said Mironov.



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