RE: DMAE, any known negative side effects?

Roderick A. Carder-Russell (
Wed, 9 Apr 1997 16:19:52 -0400 (EDT)

On Wed, 9 Apr 1997, Crosby_M wrote:

> I have seen no references to any negative side effects for DMAE.
> Remember, the result of taking DMAE is to increase the amount of
> choline available to the brain

I'm not certain that this is entirely true. It does operate in
the cholinergic system, but I don't believe that it is ever synthesized
into choline, I believe it is synthesized directly to acetylcholine. That
is why DMAE is better than choline, they have the same function, but DMAE
more effectively crosses the blood-brain barrier.

> AND choline is a natural substance
> produced in the brain, so it's not like it's really a drug, it's more
> like a 'vitamin supplement' for the brain.

Many vitamin supplements can cause harm. Look to ascorbic acid as
one examample of a highly used yet still potentially dangerous supplement.
To much ascorbic acid can cause kidney stones in the long run, and ulcers
as well.
Just because it is "natural" doesn't make it safe...
I do agree in regards to the safety of DMAE however, I have not
seen any reports of negative side affects.

> DMAE is often combined with B vitamins in
> prepared capsules.

B-5 is the most crucial.

> For stronger effects, I think the recommendation
> 300 mg per day in three doses.

I believe that is correct.

Roderick A. Carder-Russell
Student-Computer Science, Philosophy
Specializing in Man-Machine Symbiosis
Suspension Member-Alcor Foundation
Information Systems Consultant-Technology Syllogistics