SV: Re: AGING: List Members Experiences with Melatonin?
=?ISO-8859-1?Q?Per_=C5strup_Olsen?= (kinksfan@post12.tele.dk)
Sun, 23 Aug 98 06:31:21 PDT
>Tak for brevet, Jacob
Hej med travle taster, Per.
> GBurch1@aol.com writes:
>
> > There's no question in my mind that melatonin works well to reset your clock
> > and induce sleep with no after-effects of next-day grogginess.
>
> This is my (extremely limited, two data points) experience too. It
> does wonders with jet-lag, and this is a well documented area.
>
> > I can't speak to the potential for broader systemic benefits, since I
> haven't
> > done a control with a clone :-) I'm unaware of any long-term rigorous
> > experiments that are being done, but I'm someone is carrying out such
> > research. I would be very curious to see the results of any such studies.
>
> So far there is no good scientific evidence for life extension; lots
> of intriguing hints and studies that can be doubted, but no evidence I
> would bet on.
>
> See for example
>
> @article{Brzezinski97a,
> author = {A. Brzezinski},
> title = {Melatonin in humans},
> journal = {N Engl J Med},
> volume = {336},
> number = {3},
> pages = {186--95},
> month = {Jan 16},
> year = {1997},
> keywords = {Aging/physiology Animal Circadian Rhythm/physiology Female
> Human Male Melatonin/immunology/*physiology/secretion
> Neoplasms/physiopathology Pineal Body/secretion Puberty/physiology Receptors,
> Cell Surface/physiology Reproduction/physiology Sleep/physiology}
> }
>
> He mentions that it *may* enhance immune response, protect against
> tumors and influence sexual maturation. The antioxidant effects are
> likely only in pharmacologic concentrations, not in the ordinary
> concentrations.
>
> Personally, I will likely only use melatonin to fix jet lag until I
> notice that my leves start to decrease overly due to aging.
>
> --
> -----------------------------------------------------------------------
> Anders Sandberg Towards Ascension!
> asa@nada.kth.se http://www.nada.kth.se/~asa/
> GCS/M/S/O d++ -p+ c++++ !l u+ e++ m++ s+/+ n--- h+/* f+ g+ w++ t+ r+ !y
>