From: Emlyn O'regan (oregan.emlyn@healthsolve.com.au)
Date: Sun Sep 14 2003 - 18:20:18 MDT
That looks like a strong approach. Tough work!
There seemed to be a concern that the cells, which have the telomerase and
ALT pathways knocked out (through unspecified means? How are they originally
knocked out?), might turn those pathways back on (although this is
addressed). Why not target the immune system against telomerase, at least,
as in this article:
http://psa-rising.com/medicalpike/vaccine-telomerase-ucsd-april2000.htm
This may in fact be what the intention is; get the immune system to kill off
all cells with telomerase turned on (ALT dealt with seperately), then
periodically reintroduce stem cells with telomerase off but with long
telomeres.
Emlyn
> -----Original Message-----
> From: Aubrey de Grey [mailto:ag24@gen.cam.ac.uk]
> Sent: Sunday, 14 September 2003 11:15 PM
> To: extropians@extropy.org
> Cc: ag24@gen.cam.ac.uk
> Subject: RE: cancer rates
>
>
>
> Robert is doing a great job explaining the current undestanding of
> cancer and why it is so hard to combat; I wish I had the time to
> be more expansive myself but I have a small conference coming up.
> All I have time to say right now is that there is a way out of the
> "mess" that Robert describes, which is outlined at:
>
> http://www.gen.cam.ac.uk/sens/SENS3.htm
>
> Questions and challenges are of course welcomed, but answers may be
> delayed until Sept 24th.
>
> Aubrey de Grey
>
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