STEM CELLS: Scientists Create Britain's First Stem Cell Line :-)

From: Brett Paatsch (bpaatsch@bigpond.net.au)
Date: Wed Aug 13 2003 - 09:37:13 MDT

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    Extropes,

    This is a *good* thing!

    STEM CELLS: Scientists Create Britain's First Stem Cell Line

    (link below)

    Reason. 1. The UK which (now) has the worlds most liberal
    stem cells laws (excepting perhaps China and those that don't
    really have laws) but was not as advanced as other places
    (like the US and Australia) has now caught up (or imo) even
    passed the high water mark set by these countries.

    Reason 2. The cell lines will be available to researchers
    unencumbered. Think open source in terms of accelerating
    rates of understanding. Think less toll gates on the product
    development highway.

    Reason 3. Because embryos are allowed to be created to
    around the 5 day stage from people known to have diseases
    (such as Parkinson's) etc. The resulting stem cell lines (cells
    taken from the Inner Cell Mass of the blastocyst (= 5 day
    old embryo) can give vital clues into the how a genome with
    Parkinson's develops. And thereby offers better (more
    focussed, cheaper, quicker) drug discovery.

    As Robert Bradbury is wont to say on occasion. Today
    is a good day to be an extropian :-) - and a person.

    Regards,
    Brett

    -----------
    STEM CELLS: Scientists Create Britain's First Stem Cell Line

    http://story.news.yahoo.com/news?tmpl=story&u=/nm/20030813/sc_nm/health_britff t
    ain_stemcells_dc_2

    "LONDON (Reuters) - Scientists said on Wednesday
    they had created Britain's first human embryonic stem
    cell line, clearing the way for more research into
    diseases including diabetes and Parkinson's.

    The team, at King's College London, said the new line
     -- a string of many identical cells -- would be deposited
     in the Medical Research Council's $4.2 million stem cell
    bank, which was launched last year.

    Stem cells hold the promise of treating a range of medical
    conditions but their use is controversial because although
    they are found in adult tissue, the most flexible stem cells
    come from early embryos.

    In this case, the researchers said they obtained three stem
    cell lines from 58 embryos. Two cell lines perished but the
    remaining one had now been growing for many months.
    "We are very excited about this development," said Dr
    Stephen Minger, one of the leaders of the team whose
    work was published in Reproductive BioMedicine Online.
    "Human embryonic stem cells are found in the earliest stages
    of development and are capable of giving rise to all the
    different types of cell in the body. This means their possible
    therapeutic uses are almost endless."

    Minger told Reuters the researchers were particularly
    interested in research aimed at generating new cells for
    transplantation in diabetes and Parkinson's disease .. and
    possibly also for patients with heart disorders.

    Traditionally, stem cell lines have been created with great
    difficulty using cells from embryos surplus to IVF, which
    are often of poor quality. But in this case, high-quality
    embryos were donated by women undergoing pre-
    implantation genetic diagnosis because they were known
    to be at risk of passing on serious genetic disorders if they
    had children.

    Only embryos unaffected by these disorders were replaced
    into the women. Cells from the remaining embryos, which
    were unsuitable for replacement and would normally have
    perished, were used to generate the stem cell lines.

    The Kings College team was one of the first two laboratories
    in Britain to be granted a license by the Human Fertilization
    and Embryology Authority to generate human embryonic
    stem cells.
    ----------

    Regards,
    Brett Paatsch



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