From: Alex Ramonsky (alex@ramonsky.com)
Date: Sat May 31 2003 - 05:52:54 MDT
Damien Broderick wrote:
>
>Hang on. Isn't that "memoriz*ing* information switches one's genes on and
>off"?
>
>
Yes. Gene expression is initiated by CREB (cAMP response element binding
protein), which is activated by AMPA receptor proteins, that have been
phosphorylated (had a phosphate group added), by kinases that travelled
to the cell nucleus, because they were activated by calcium influx at
NMDA receptors opened by glutamate, because the action potential of
cells firing removed the magnesium block on them, and the likelihood of
cells firing was increased in the first place by the reception of
glutamate at postsynaptic AMPA receptors, because you released glutamate
from the presynaptic neuron when you encountered the sensory input. It's
how LTP happens. Remember?
Ramonsky
>Damien Broderick
>
>
>
>
>
This archive was generated by hypermail 2.1.5 : Sat May 31 2003 - 05:57:07 MDT