HEALTH: Regulome mapped

From: Robert J. Bradbury (bradbury@aeiveos.com)
Date: Fri May 30 2003 - 10:16:53 MDT

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    Well, in a stunning piece of work (to me) researchers
    at Washington University School of Medicine have mapped
    the yeast "regulome".

    "Yeast Genomes Reveal New Sites of Gene Control"
    http://www.sciencedaily.com/releases/2003/05/030530082133.htm

    This is important because it now means that we have most,
    perhaps all, of the regulatory sequences and sites for producing
    eukaryotic cells (the building block of all higher organisms)!

    Because it has been demonstrated this is feasible, it will
    only be a matter of a few years (perhaps 3) before it is
    probably repeated for organisms (using perhaps human, mouse,
    rat, pig, cow and chimpanzee genomes) so we will have the
    regulome of mammals (and us). This will be critical to
    understanding multi-cellular, and multi-tissue type and
    even organ development. That in turn will allow the
    construction of genomes to rapidly generate specific organs.

    For the programmers on the list the regulatory sequences
    in the DNA and the genes that bind to them and regulate
    them are the "conditional statements" of the genomic
    programs. From an Andre Norton "Witch World" point
    of view -- to me this is like knowing the name of
    something -- that in turn gives you power over it.

    So, to extropians, "today should be a *good* day to live".

    Robert



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