Brain stimulation (Was: Parallel Universes)

From: Anders Sandberg (asa@nada.kth.se)
Date: Tue Feb 11 2003 - 11:58:31 MST

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    On Tue, Feb 11, 2003 at 09:30:11AM -0800, Ramez Naam wrote:
    >
    > From: Eliezer S. Yudkowsky [mailto:sentience@pobox.com]
    > > I've never heard of this result. Got ref?
    >
    > Lee, I think you may be referring to work done in the 1950s and 60s by
    > Jose Delgado. Delgado reported that he could relieve extreme pain, as
    > well as many of the symptoms of schizophrenia, by stimulating the
    > "septal pleasure centers" electrically. He describes this in his book
    > _Physical Control of the Mind: Towards a Psychocivilized Society_
    >
    > However, in that book he never talks about the patients having the
    > ability to self-stimulate.

    It could be Robert J. Heath in New Orleans; he did similar stuff, and I
    seem to recall that he did experiment with self-stimulation. But I do
    not recall any pain treatments, mostly attempts to deal with violent
    outbursts and psychosis.

    > Eliezer, I'm not sure if you were asking Lee about this result in
    > humans or the result in rats. The result in rats was produced by Olds
    > and Milner in 1954. Rats will indeed self-stimulate to the exclusion
    > of food and water, even up to death. (They do the same thing with
    > cocaine and amphetamines.)

    Actually, the self-stimulation to death factoid is not really true. It
    depends a lot on the experimental setup and in most cases they make a
    tradeoff. See the work of Peter Shizgal, e.g.
    http://cogprints.ecs.soton.ac.uk/archive/00000740/

    "On the neural computation of utility: implications from studies of
    brain stimulation reward"

    -- 
    -----------------------------------------------------------------------
    Anders Sandberg                                      Towards Ascension!
    asa@nada.kth.se                            http://www.nada.kth.se/~asa/
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