From: Robert J. Bradbury (bradbury@aeiveos.com)
Date: Tue Jan 28 2003 - 19:23:42 MST
On Tue, 28 Jan 2003, Joao Magalhaes wrote:
> I finally had a chance to read the paper and, as Robert noticed, the
> increase in longevity is still far from that witnessed in CR.
[snip]
I had the opportunity to witness the presenation by David Harrison today [1]
for which I had high hopes that I don't think were fullfilled. I don't think
that he made the case for his premise sufficiently.
However, he did bring up some of the IGF/GH/CR topics/issues extensively with
regard to various strains of mice. This seems pretty unavoidable at this point.
Energy consumption and/or the regulation of energy consumption does seem to effect
longevity.
Joao makes some very valid points regarding other physiological changes
that take place under CR. I think the message here may be that aging
is a multi-factorial process (as the evolutionary biology of aging perspective
would suggest). So "low fat reserves" may translate into some
extenstion in longevity. Then we want to know *why* that is the case
and what else are we missing to explain the complimentary longevity
extending effects.
Robert
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