Re: AGING: mammalian lifespan extension-IGF-1-colostrum-citations

From: Extropian Agro Forestry Ventures Inc. (megao@sk.sympatico.ca)
Date: Mon Jan 13 2003 - 20:20:56 MST


http://www.marysgarden.com/colostrum/growth_factors.htm

Q-can oral colostrum IGF-1 survive digestion and successfully pass the gut?
can microencapsulation achieve the first hurdle?
Can peyer's patch (sp)or other portion of gut snag this protein (pt2)?

.. MJ

otherwise other means to stimulate optimal levels are required...

"Robert J. Bradbury" wrote:

> Looks like they have a concrete model for lifespan extension
> in mammals (F: 33% / M: 16%) in partial IGF-1R knockout mice.
>
> See:
> Cost-free longevity in mice
> Nature 421:125-126
> http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v421/n6919/full/421125a_fs.html&content_filetype=pdf
>
> and
>
> IGF-1 receptor regulatses lifespan and resistance to
> oxidative stress in mice.
> Nature 421:182-187
> http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v421/n6919/full/nature01298_fs.html&content_filetype=pdf
>
> Robert



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