From: Doug Skrecky (oberon@vcn.bc.ca)
Date: Sat Jan 04 2003 - 12:41:02 MST
This is the 77'th update of my fly longevity experiments. Average
temperature was 25.1 C during this run. Here I take another look at
combinations of acetyl-L-cysteine (ALC), and some antioxidants.
Once again lipoic acid at 100 mg looked to be slightly useful, but
acetylcysteine is a dud, and melatonin is so-so. The reader might ask why
I'm still looking at ALC combinations, when previous results were so
uninspiring. This is because this, (and the next) run were started before
the results from previous runs were available. In order to facilitate the
speed that results can be obtained, up to ten runs may be in progress
simultaneously.
Run #77 Percent Survival on Day
supplement 4 9 16 21 28 34 39 45 51 56
_________________________________________________________________
control 88 56 50 44 38 19 0 - - -
ALC 125 mg + lipoic 100 mg 93 80 47 47 40 27 20 13 0 -
ALC 125 mg + lipoic 200 mg 90 57 38 38 24 14 5 0 - -
ALC 125 mg + lipoic 400 mg 94 55 45 39 21 15 15 6 3 0
ALC 125 mg + acetylcysteine 125 mg 92 52 12 8 4 4 0 - - -
ALC 125 mg + acetylcysteine 500 mg 100 40 30 20 15 10 0 - - -
ALC 125 mg + melatonin 10 mg 93 41 30 30 15 7 0 - - -
ALC 125 mg + melatonin 40 mg 100 57 33 38 29 24 19 10 0 -
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