Re: Blue Gene

Eugene Leitl (
Mon, 6 Dec 1999 14:46:40 -0800 (PST)

John Clark writes:

> True, in fact very few problems are is hard as protein folding, that why I was so
> impressed. I think it's interesting that until about a decade ago biology was the
> only area of scientific research where computers did not play a major part, now
> the largest computer of all (by far) will be engaged in it exclusively.

It should be pointed out that having 'merely' sufficient performance is not enough: current force fields are not accurate by far to solve PFP brute-force. If you distort the target structure randomly, minimally, it almost never comes back. With current force fields.