From: sbharris@ix.netcom.com(Steven B. Harris) Newsgroups: sci.med.nutrition,misc.health.alternative
There's another problem with interpreting rodent DHEA experimental results, and that is the fact that DHEA causes proliferation of liver peroxisomes in rodents, but apparently does not do so in humans. This proliferation of these organelles which are full of nasty oxidative enzymes is thought to underlie the hepato-carcinogenic effect of the stuff in rodents. So it's not at all clear that humans are at the same risk, even with the same megadose of DHEA.
Steve