Re: CRYOprotectants: Notes of an amateur

Anders Sandberg (
16 Dec 1997 15:32:08 +0100

Twink <> writes:

> Protein: Anders mentioned some proteins denature. I'm not
> sure if this is because of low temperatures, interaction with cps or
> some other process(es).

I got this from Mike Darwin. Obviously some cps do it, but it seems to
be a temperature phenomenon too.

> Other:
> Note tolerance level to cp.
> Does it cause any damage?
> More than one cp?
> Is a cp "cocktail" better than one cp?

The problem is the combinatoric explosion of the search space.

> Perhaps different cps should be used for different
> tissues?

Problem: how do you get them there?

> Perhaps different cps should be used at at different
> times in the process?

Sounds like a good idea.

> What is its long term optimal working temperature?

Irrelevant, since its only purpose is to limit tissue damage doing
suspension. Of course, if it caused continuing damage at -170, then it
would be a concern, but that is rather unlikely.

> Design of "home" cryonics kit for use in emergency situations.
> (This involves messy legal issues, but the design of
> one might lead to a wider acceptance of cryonics by
> making it a fait accompli.)

A fun idea. I can see before me "The Little Cryonicist" for kids:
suspend your pet (liquid nitrogen not included). Not very likely to
work, though, since it likely requires medical expertise.

Anders Sandberg                                      Towards Ascension!                  
GCS/M/S/O d++ -p+ c++++ !l u+ e++ m++ s+/+ n--- h+/* f+ g+ w++ t+ r+ !y