Eugene Leitl's work on ice blockers

Eugene Leitl (
Wed, 29 Sep 1999 22:11:16 -0700 (PDT)

Jeff Davis writes:

> Eugene, you've hinted at this a couple of times recently. If you can do so
> without giving away the store, perhaps you might elaborate a bit.

Oops <blush>... er... As you perhaps know, Mr. Darwin is prone to lapsing into dramatic narratives. The hours are not as long as depicted, nor the new iceblockers as good as advertised. Since the already disclosed methoxylated stuff quite good progress has been made; my contribution however belongs more into the cathegory "minor tweaks".

In toto, with the new cryoprotectants it looks as if reversible organ cryopreservation is not just a pipe dream anymore (surprise, surprise). Perhaps in a few months we will know more, when the kidney work will move into new phase (enough tox studies on slices, let's go for the whole hog). Inasmuch the new iceblockers translate into improvement for brain vitrification, remains to be seen. However, we landed just a random hit in structure space, it is unlikely to be the global optimum. There should be much better things out there.

More news to follow, film at eleven..

> And if you can't, well, thanks for the effort, congratulations on your
> accomplishment, and keep up the good work.

I'd love to tell everything I know, unfortunately the patent agencies' mills grind quite slowly. I don't know how much I can disclose without blowing the claims, so I better keep quiet.

Thank you for your kind wishes!