Re: NANOMED: [was Weekend tidbits~ Nanogirl News.]
Mon, 6 Sep 1999 13:03:55 EDT

In a message dated 99-09-06 12:54:34 EDT, (Robert J. Bradbury) wrote:

> [An interesting side-note here is that we are discovering interesting

> therapeutic uses for biochemical processes developed by the HIV virus...
> Dowdy's work is using the HIV TAT protein fragment to introduce a
> carefully engineered protein that causes cell death if and when the cell
> becomes infected with HIV. This new protein effectively functions as a
> "trojan horse". Very very slick work.]

A probably naive question: Are these mechanisms exploitable to do wholesale somatic cell genetic engineering, i.e. can a retrovirus be tinkered with to be a vector to carry specified genome "edits" into lots and lots of (targeted?) somatic cells?

     Greg Burch     <>----<>
     Attorney  :::  Vice President, Extropy Institute  :::  Wilderness Guide   -or-
                         "Civilization is protest against nature; 
                  progress requires us to take control of evolution."
                                      -- Thomas Huxley