Dear Natasha (and everyone else):
I've been away for a while, and am now trying to play a little catch-up. Your point(s), Natasha, is(are) well-taken. I'm curious, though, as to precisely what, in your judgment, female proto-transhumanist memes consist of, as distinguished from male-originated memes.
As for female "Ancestral [proto-]Extropians," well there's Ursula K. LeGuin, perhaps Marilyn Ferguson, arguably Barbara Marx Hubbard, the more-or-less libertarian feminist Valentyne LeClaire...that's about all I can think of right off the top, but it's a start!!