I spent a year contemplating this question. It is one of the deepest spritual issues. It is the issue of Quarantine.
It is my belief that the answer to this issue relates to holistic perception over spacetime and levels of group mind.
In Extropian terms, at what point in the evolution of life on Earth would you have intervened and provided boosting were you a post-Escalation/Spike/Singularity being? Immediately, unless some version of Tipler were correct.
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29 after Armstrong