http://www.sunday-times.co.uk/news/pages/sti/2001/08/26/stinwenws01021.html
< The project studied the genes of 137 100-year-olds, and those of their
brothers and sisters aged between 91 and 109, to look for genes they had in
common. The search identified a section of "chromosome four" that appeared
to be the same in all the old people. It is believed to contain up to 10
crucial disease-fighting genes.
The results of the research, which was led by Thomas Perls, a geriatrician,
and Lou Kunkel, a geneticist at the Howard Hughes Medical Institute, is
being published by the National Academy of Sciences in America tomorrow.
It derived from research on fruit flies which has shown that there are only
a few genes that need to be altered to increase lifespan markedly. The team
correctly assumed that a painstaking comparison of human gene profiles
would lead to the discovery of similar factors in humans. >
etc
Damien Broderick
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