Re: life extension advocacy plans (fear of Tithonus) --> worryingaboutthebrain

Date: Tue Jul 10 2001 - 10:22:14 MDT

In a message dated 7/10/01 8:31:10 AM, writes:

>This prompts me to ask the question: Is exercise an equivalent alternative
>to CR? Or is it better to avoid excess calories in the first place rather
>than burn them off later?

Exercise is not equivalent to CR in mice. With mildly restricted (30%
from ad lib) mice it's almost as good. Further CR, however, produces further
lifespan benefits, while further exercise does no good at all. It's not clear
how the breakpoint translates into humans; we have no idea what a 30%
calorie reduced mouse corresponds to. Exercise has not been shown to have
significant health benefits in people who can do passable aerobic exercise
and who aren't overweight.

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