Transposon Gene Therapy...

From: Corbally (icorb@indigo.ie)
Date: Tue Aug 22 2000 - 15:35:12 MDT


Nice idea this....

http://unisci.com/stories/20003/0822004.htm

>Scientists led by Eric Wickstrom, Ph.D., professor of microbiology and
>immunology, and graduate research assistant Stephen H. Cleaver, both of
>Jefferson Medical College and Thomas Jefferson University in Philadelphia,
have
>used DNA and bacterial proteins to deliver a gene to a specific place in a
piece
>of human DNA.
>
>They have used a "transposon" -- a naturally mobile piece of DNA -- from
the E.
>coli bacterium as a gene delivery vehicle, inserting a gene for antibiotic
>resistance into a segment of DNA.
>
Also...
>"It avoids using viruses that cause immune reactions, it puts the gene in a
>precise, known location as opposed to anywhere in the cell's DNA, and it
makes
>only one copy," Wickstrom says.

Maybe things are looking up for gene therapy!

Regards,

James....

 
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