Re: Cornering the causes of aging (was Re: AGING: Accumulation of DNAdamage)

From: phil osborn (philosborn@hotmail.com)
Date: Sat Jul 01 2000 - 23:30:54 MDT


>From: "CYMM" <cymm@trinidad.net>
>Subject: Re: Cornering the causes of aging (was Re: AGING: Accumulation of
>DNAdamage)
>Date: Wed, 28 Jun 2000 14:35:37 -0400
>
>CYMM SAYS: Curt, you're right of course...clumsy English again! But the
>"incompatibility" is really (i) diminishing (cost/benefit) returns to
>maintaining reproductive ability when viable progeny is extant... and (ii)
>the negative benefits of loading the genepool with archaic combinations in
>the face of rapid environmental change....
>
Nicely put. Wish you had been available twenty years ago to debate the then
gurus of life extension. This was also W. Donner Denkla's position, BTW,
but the problem was that the prior generations couldn't think very well in
terms of "systems." They refused to see beyond the genetic driving force of
the individual survival. Thus, they utterly rejected out-of-hand any
arguments for the existence of a "death gene," or "aging clock." Thus, no
research followup on Denkla's work.
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