Re: Mercury Risk - More

From: Ian Goddard (Ian@Goddard.net)
Date: Fri Mar 23 2001 - 20:00:42 MST


At 08:34 PM 03/23/2001 -0500, I wrote:
>At 08:46 AM 03/07/2001 -0800, Christopher Piersol wrote:
>
>>big one!). A study reported the simple fact of the
>>forementioned concentration levels. To be really
>>scientific, of course, there should be more studies,
>
>
> IAN: I found and acquired another study on the effect
> of mercury vapor on brain tubulin, which is what the
> last study I posted was exploring and it found that
> mercury vapor (Hg0) acted like Alzheimer's disease
> (AD) at levels one could expect if you have many
> "silver" amalgam fillings. That abstract is here:
>
> Neurotoxicology 1997;18(2):315-24
>http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9291481&dopt=Abstract
>
> The new study, a review of studies, has no abstract
> on-line, but I got it at the National Library o Meds.

  IAN: I sent that moments after collating
  and stapling copies from my last NLM visit
  and did not yet notice that the new study
  is by the same authors as the first. But,
  the second is a review of a larger body
  of research than just the first study.
  This was published in "Metal Ions in
  Biological Systems," volume 34, 1997,
  Institute of Inorganic Chemistry,
  University of Basel, Switzerland.

> Met Ions Biol Syst 1997;34:461-78
>http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9046580&dopt=Abstract
>
> This study reports that mercury prechelated with EDTA,
> EGTA, or glutamine "selectively abolishes tubulin-GTP
> interactions in normal human brain tissues." Apparently
> mercury can become chelated to glutamine in the brain.
> Such diminished GTP interactions are a biomarker of AD
> and is the same harmful effect found in the first study.
>
> The study concludes: "The data found in the references
> used in this presentation demonstrate that exposure to
> mercury causes the same aberrancy in non-AD brain and
> rat brain as observed in AD brain. These results do not
> prove that mercury causes AD. They do strongly suggest
> that exposure to mercury, and especially mercury vapor,
> would exacerbate the condition clinically defined as AD.
> Therefore, individuals with family histories indicating
> a genetic predisposition toward AD should avoid any
> exposure to mercury." I've never that important info
> anywhere except as resulting from my PubMed searches.
> One constantly finds info there you don't get elsewhere.
> The American Dental Association continues to claim that
> there is NO evidence of any risk associated with amalgam.
>
>-------------------------------------------------------------
>Visit Ian Williams Goddard ---> http://www.erols.com/igoddard
>_____________________________________________________________
>
> "The more restrictions and prohibitions in the world,
> the poorer people get." Lao Tzu (Tao Te Ching)
>
>
>
>



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