Re: SSRIs and sudden grief

From: Eliezer S. Yudkowsky (
Date: Fri May 12 2000 - 15:22:43 MDT

Damien Broderick wrote:
> At 01:01 AM 12/05/00 EDT, Mitch wrote:
> >Just the regular seratonin re-uptake inhibitors
> As I understand it these take a couple of weeks to take effect. And often
> have disturbing side effects. Not much use in fits of sudden despair.

I haven't heard any reports from anyone who's actually tried it - I gave
up on pharmeceutical fixes before I worked around to noradrenaline - but
noradrenergic reuptake inhibitors, such as Reboxetine and Edronax, might
be worth a shot.

MAO inhibitors (Monoamine Oxidase, silly, nothing to do with China) are
supposed to have an effect on serotonergic, dopaminergic, AND
noradrenergic systems; literally make you start dancing on clouds.

In general, a good place to check out this sort of thing is the highly
transhumanistic "Good Drug Guide" by David Pearce.
(Section on Reboxetine:, who knew.)

If that doesn't work, you could try happiness. Many people report that
happiness is surprisingly effective in combating despair; similar
results have been reported for joy.

And if *that* doesn't work, remember: The four steering wheels of the
mind are will, belief, reflex, and expectation. If your will is broken,
you just have to learn how to alter belief, reflex, and expectation.

--      Eliezer S. Yudkowsky

                 Member, Extropy Institute
           Senior Associate, Foresight Institute

This archive was generated by hypermail 2b29 : Thu Jul 27 2000 - 14:11:10 MDT