p21 gene

From: Damien Broderick (d.broderick@english.unimelb.edu.au)
Date: Tue Apr 11 2000 - 22:44:30 MDT

>Today CNN carried a story about an aging gene called p-21 that is responsible
>for expressing aging related disease genes

p21 is, the web tells me (with various further hotlinks) at


< a cyclin-dependent kinase inhibitor 1. Induced by p53, and may mediate
its role in response to DNA damage. >

p53 is one of the most famous genes linked to cancer, since it inhibits
transformation into the malignant state except when damaged. So p21 must be
part of a control feedback loop. Robert?


This archive was generated by hypermail 2b29 : Thu Jul 27 2000 - 14:09:14 MDT