Genetics web pointers for Max More and others interested

Gregory Sullivan (
Wed, 12 Mar 97 16:23:28 EST

Max More says:
>I'm compiling a list of technologies that accelerate overall technological
>progress, especially those technologies most relevant to augmenting the
>human body and brain. The list also includes creative machines, i.e.,
>software that generates novel results. My existing list follows. I'd
>appreciate any suggested additions or details on things already listed (or
>places where I can find the details, preferably on the web).

>DNA chips for testing sequences of DNA to determine function. (Also
>positional cloning to discover disease-causing genes and maybe
>ability-carrying genes.)

Red Herring has an article from December 1996 which
discusses Affymetrix and Nanogen

Affymetrix has a web site

Nanogen may have a web site but I can not find it.
(The following URL for Nanogen is given in the Red Herring
article but does not seem to work)

There is a profile of Synteni Inc at HMS Beagle
(requires a free registration to access)
The profile of Synteni is pointed to from
the home page of HMS Beagle currently but will
probably move to an archive soon at:

Synteni, Inc

Profile of Affymax, the parent company of Affymetrix

Affymax is now part of Glaxo Wellcome

There is an article in Wired by former list member Ed Regis
Hacking the Mother Code

There is an article in the March 1997 Scientific American on
the powerful technique of gene tagging. Unfortunately, the article
is not on the web.

Discovering Genes for New Medicines
William A Haseltine

The authors company is Human Genome Sciences (HGS)

>3-D modelling of biochemistry.

InScight has a short shallow summary of two recent papers in Nature which
are about determining the structure of a protein (hepatitis B virus core
protein (HBc)). The Nature articles are interesting because of:

the novel technique the researchers used to derive the protein's
structure--an electron microscope rather than the old standby, x-ray
crystallography--heralds a new approach to resolving the structure
of molecules that resist forming crystals.

InScight article title: "A Sharper View of Hepatitis B"

Unfortunately, the Nature articles can not be read on the web without an
expensive subscription I believe.

Gregory Sullivan