From: Anders Sandberg (asa@nada.kth.se)
Date: Sat Jul 12 2003 - 05:44:58 MDT
[ Inspired by the mosquitos of New Haven and Kalix :-) ]
What to do about mosquitos? Besides being terribly irritating, in many 
places they transmit dangerous diseases. While chemical repellents work 
to some extent they might be too costly for the thrid world, have toxic 
side effects and need to be applied regularly. Insecticides work better, 
but often cause ecological disruption . mosquitos are an important part 
of the ecosystem. Spreading sterile mosquitos to cause a decline in 
population is costly, since the numbers of mosquitos are so large.
On the more radical side, it ought to be possible to genetically 
engineer mosquitos to avoid humans. But how to introduce such genes into 
the mosquito population and make them dominant? A possible approach 
would be evolutionary: introduce an evolution pressure on the mosquitos 
to avoid humans.
My suggestion is along these lines: many people take pills that contain 
a substance that acts as a mosquito contraceptive. Mosquitos that bite 
such people will be less fertile, and hence not pass on their genes to 
the next generation. Mosquitos that tend to avoid humans will have more 
offspring and become more common. Over the next generations mosquitos 
will become increasingly human-friendly.
Will this work? It depends on whether it is possible to create a cheap 
substance acting as an insect contracpetive that stays relatively long 
in the human body and does not cause side effects. Enough people need to 
take it to make the fitness of human-biting mosquitos less than 
human-avoiding mosquitos (human-avoiding mosquitos probably currently 
have a slightly smaller fitness since humans are common, large and 
well-fed mammals in most environments). The larger the fitness decrease, 
the faster the evolution towards the avoiding form. The behavior also 
needs to be changeable; this seems likely since many insect parasites 
are species-specific.
Some drawbacks are: There might be an evolution towards contraceptive 
resistance rather than non-biting. Ideally different pills should 
contain different contraceptives making such resistance unlikely and 
evolutionary harder than evolution towards non-biting.
Humans need to continue taking the pill to keep the selection pressure 
up. If they stop human-biting mosquitos will start to increase again. 
There will also be an influx of such mosquitos from regions where the 
pill is not commonly used (while non-biting mosquitos will move into 
these regions). This might lead to a tragedy of the commons problem, as 
mosquito protection is a public good but the slight discomfort/cost of 
the pill makes people want to avoid it . unless of course taking the 
pill can also be made to benefit them too. Maybe the mosquito 
contraceptive should be packaged together with a nutrient supplement of 
some kind? In general the logistics and the economics of this 
evolutionary approach to mosquitos needs to be studied a bit more 
closely. The principle seems to be fairly simple and robust, but the 
actual implementation might be done in many different ways. 
What do you think?
-- ----------------------------------------------------------------------- Anders Sandberg Towards Ascension! asa@nada.kth.se http://www.nada.kth.se/~asa/ GCS/M/S/O d++ -p+ c++++ !l u+ e++ m++ s+/+ n--- h+/* f+ g+ w++ t+ r+ !y
This archive was generated by hypermail 2.1.5 : Sat Jul 12 2003 - 05:50:12 MDT