Eating glycotoxins

From: Brian Atkins (brian@posthuman.com)
Date: Mon May 12 2003 - 17:48:48 MDT

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    Recently, LEF article says eating glycotoxins (AGEs) in diet increases
    them in your bloodstream, and also causes inflammation (C-reactive
    protein, etc.).

    http://www.lef.org/magazine/mag2003/may2003_awsi_01.html
    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12429856&dopt=Abstractõt
    (anyone have access to this? I'd love to read the whole thing)

    So I'm interested in finding a data source on glycotoxin content of
    various kinds of foods. Anyone have data on that?

    While I was searching, I did run across papers below that say eating
    fructose may dramatically increase glycotoxin production in the body.

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11876491&dopt=AbstractÂu
    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12234125&dopt=AbstractÃu
    http://www.biomed.cas.cz/physiolres/2002/issue3/pdf/krajcovic.pdf

    So what's more important? Dietary content of glycotoxins, or
    glycotoxin-promoting substances? Is it possible to come up with a
    healthy diet that will minimize both, and also keep blood glucose and
    insulin levels low?

    Other questions:

    Do alternate metabolism processes such as ketosis cause more or less
    glycotoxin formation vs. standard glucose metabolism?

    The LEF article mentions in passing that cooked meats have accelerated
    glycotoxin formation because they also contain "bad fats". I thought
    only proteins and sugars were involved in the process.. can anyone explain?

    Recent news says ACE inhibitor drugs help prevent glycotoxin formation,
    and Metformin in a CR-mimic (potentially add 15 years to your life or
    more... maybe). Anyone considering adding these into their health
    regimen? Any doctors known to be proscribing them for these purposes?

    -- 
    Brian Atkins
    Singularity Institute for Artificial Intelligence
    http://www.singinst.org/
    


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