On Saturday, September 16, 2000 11:46 PM Eugene Leitl
eugene.leitl@lrz.uni-muenchen.de wrote:
> > viable business plan around. No one, to my knowledge, is using them
for,
> > say, e-commerce or web development.:)
>
> I would use them for computer securety. As soon as someone will breed
> a good suite to breed assembly, and 3l33t h4x0rs start using it, you
> can assume the global networks will break down for a good long while.
Not a bad idea.
> > Anyone interested in doing that here? (I've mentioned this on the list
> > before, in regards to testing the space of cryoprotectants. But this
was
> > about two or three years ago. I think only Anders Sandberg responded.)
>
> The idea is not new,
I mkae no claims to originality here.
> and I've indeed have been looking at the HIC-UP
> database to seed the initial population pool, but there are technical
> difficulties involved with simulating this in the computer. The
> current water models are no damn good, and cryoprotectants do a lot of
> subtle things with hydrogen bridge bonds, and bonding to ice nuclei
> (diffusion is slow), and also see the necessary simulation volume and
> time scale.
I'd say we can start with a bad model and see if we get any interesting
results from it. Someone can then test results in the lab.
> The problem of finding a cryoprotectant mix which will
> vitrify at concentrations low enough to be nontoxic is solved,
> anyway. What is left to do is the problem of putting the kidney back
> into the donor animal, after cycling it through the whole
> extraction-flushing-loading-chilling-vitrification-devitrification-
> unloading-implantation ordeal, and have it survive in better than
> few 10% of all cases.
I don't disagree, though finding even better cryoprotectants should not be
overlooked. Plus, you've set new problems to be solved, which can, I
believe, be solved against the space of cryoprotectants using GA. That is,
cryoprotectants which flush well.
Cheers!
Daniel Ust
http://uweb.superlink.net/neptune/
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