At 02:15 AM 21/08/00 -0400, Don Klemencic wrote:
>It appears that the 'dark side' of
>telomerase is manifested only when cells regain telomerase after having been
>previously damaged by its absence.
I'd have thought: more often, damaged in certain relevant oncogenic ways by
disruptive chemicals, oxidative stress, radiation mutation, etc.
(`accelerators' jammed on, `brakes' knocked out). But it would certainly be
interesting to know how much tumor-conducive damage is caused by copying
errors and the like due to telomere erosion in frequently-replaced cells.
Damien Broderick
This archive was generated by hypermail 2b29 : Mon Oct 02 2000 - 17:36:22 MDT