"Pass it on; Mice really can inherit an artificial chromosome," New
Scientist, 08 July 8, 2000, at
"[Researchers] have shown it is possible make artificial chromosomes that can
pass from one generation to the next.
"Such techniques might soon make it possible to treat patients by loading
their cells with extra chromosomes that are purpose-built to produce a
therapeutic protein and operate entirely independently of our natural
chromosomes. It might even be possible to treat genetic diseases with extra
chromosomes that can themselves be inherited, though this would mean
challenging the taboo against 'germline' gene therapy."
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