Re : Cornering the causes of aging (was Re: AGING: Accumulation of DNAdamage)

From: Joao Pedro de Magalhaes (joao.magalhaes@fundp.ac.be)
Date: Sun Jul 02 2000 - 08:40:30 MDT


Hi!

phil osborn wrote:
>Nicely put. Wish you had been available twenty years ago to debate the then
>gurus of life extension. This was also W. Donner Denkla's position, BTW,
>but the problem was that the prior generations couldn't think very well in
>terms of "systems." They refused to see beyond the genetic driving force of
>the individual survival. Thus, they utterly rejected out-of-hand any
>arguments for the existence of a "death gene," or "aging clock." Thus, no
>research followup on Denkla's work.

I'm familiar with Denckla's work (I heard from one of his former
collaborators many interesting results they never published). However, I
heard Denckla himself is in the mountains of Virginia hearing spirits and
speaking to little green man! Is this true? Either he's a visionary or a
complete lunatic. Some species certainly have death genes in the form of
upregulating hormonal cascades; despite unlikely, perhaps human aging has
similar causes too (as I said before, I think human aging is probably a
simple mechanism).

Hasta.

---
Joao Pedro de Magalhaes
  
The University of Namur (FUNDP)
Unit of Cellular Biochemistry & Biology
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B-5000 Namur BELGIUM

Fax: + 32 81 724135
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