Re: SSRIs and sudden grief

From: KPJ (kpj@sics.se)
Date: Mon May 15 2000 - 09:24:59 MDT


It appears as if James Wilson <netsurf@sersol.com> wrote:
|
|Is paroxetine chemically related to any of the major tranquilizers
|e.g. chlorpromazine (I noticed the fluorophenyl piperidine) and that
|where the disturbing side effects come from? The older SSRI's have
|side effects (cholinergic, weight gain) but generally they didn't seem
|"disturbing" (no tardive diskinesia type as opposed to the major
|tranqs.)

I don't about the chemical relation, if any, with chloropromazine,
but I feel, after a fast peek at the chemical structures of the two,

<URL:http://www.biopsychiatry.com/chlorpromazine/index.html>, and
<URL:http://www.sb.com/prescribing_information/images/pi_scans/px16a/px16a_1.gif>

that they don't look very related to me.

I did not experience any "disturbing" side effects, just the ones expected,
such as dryness of the mouth.



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