From: LEF Email List1 [mailto:email@example.com]
Sent: Monday, May 01, 2000 6:53 AM
Subject: Life Extension Update 4-29-00
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In This Issue 4-28-00: What's Hot!---GLUTATHIONE PROTECTS AGAINST FLU,
CALCIUM FIGHTS FAT; April 2000 Magazine---HOW CoQ10 PROTECTS YOUR
CARDIOVASCULAR SYSTEM; April 2000 Medical Updates--- VITAMIN B-12
DEFICIENCY: A NEW RISK FACTOR FOR BREAST CANCER?, PLANT FOODS,
ANTIOXIDANTS AND PROSTATE CANCER RISK.
GLUTATHIONE PROTECTS AGAINST FLU
Scientists from Emory University scientists reported at the Experimental
Biology 2000 meeting that glutathione could aid in the prevention of flu
virus if applied to the mouth and throat.
Dr Jones stated, "We believe that if we put the glutathione in a lozenge,
we could directly expose the virus-susceptible tissues to glutathione over
a relatively long period of time. This could be very helpful, for example,
if you were sitting next to someone with the flu on an airplane. You could
effectively block the infection for a period of several hours . . . There
is a natural variation among people in resistance to viruses and in our
natural antioxidant system. If we are smokers, if we are deficient in
antioxidant vitamins, if we are under stress, or as we become older, we
become more oxidized, which makes us more vulnerable to viral infection.
This direct exposure to glutathione could be part of an overall strategy
to enhance our antioxidant defenses."
CALCIUM FIGHTS FAT
At the recent Experimental Biology 2000 conference researchers reported
that high levels of calcium may aid weight loss. Calcium appears to
prevent fat cells' storage mechanisms from switching on. Conversely, diets
deficient in calcium stimulate hormones that switch on the preservation of
fat within the cells.
Acting upon results suggested by an older study of obese men, a team led
by Dr Michael Zemel at the University of Tennessee, Knoxville, tested four
low calorie diets with varying levels of calcium on obese mice and kept
one group on a low calcium, high calorie regimen. Mice who received a low
calorie diet supplemented with high levels of calcium carbonate lost
approximately 42% of their body fat and one fifth of their weight,
compared to a loss of 8% body fat and 11% of body weight in mice who
received a diet similar in calorie content, but low in calcium.
April 2000 Magazine
HOW CoQ10 PROTECTS YOUR CARDIOVASCULAR SYSTEM
At least 35 controlled clinical trials in Japan, Europe and the U.S. have
demonstrated the effectiveness of CoQ10 therapy in congestive heart
failure, angina and ischemic heart disease, and myocardial infarction.
A recent animal study demonstrates the potential of CoQ10 as a preventive
therapy for atherosclerosis. Two groups of rabbits were fed a diet rich in
trans fatty acids in order to provoke elevated cholesterol and
triglyceride levels (hyperlipidemia). Later in the study, oxidants were
added to the rabbit chow to provoke lipid peroxidation. The group of
rabbits treated with CoQ10 displayed significant reductions in arterial
plaque, with less than half the
atherosclerosis score and plaque thickness in both the aortic and coronary
arteries, compared to the control group. Measures of oxidative damage also
CoQ10 deficiency is commonly seen in patients with heart failure. The
degree of deficiency corresponds to the degree of impairment in the
function of the left ventricle. CoQ10 supplements may correct this
deficiency noticeably in one to four weeks, and maximally in several
It has long been observed that CoQ10 improves the relaxation of heart
muscle (in medical terms, diastolic function). Until recent years doctors
thought that weak contraction of the heart muscle was the main cause of
heart failure, but we now know that this becomes less true with advanced
age. Aging affects the ability of the heart to relax far more than its
ability to contract. When the heart muscle cannot fully and quickly relax,
the heart does not fill properly with blood. By age 70, the rate of
filling may be only half what it was at age 30.
April 2000 Medical Updates
VITAMIN B-12 DEFICIENCY: A NEW RISK FACTOR FOR BREAST CANCER?
Full source: NUTRITION REVIEWS, 1999, Vol 57, Iss 8, pp 250-253
An increased risk of breast cancer was observed among postmenopausal
women, having low levels of vitamin B-12. This is the first observation to
suggest that B-12 status may influence breast cancer growth and therefore
may be a risk factor for breast cancer prevention that can be modified to
achieve positive results.
PLANT FOODS, ANTIOXIDANTS AND PROSTATE CANCER RISK
Full source: NUTRITION AND CANCER-AN INTERNATIONAL
JOURNAL, 1999, Vol 34, Iss 2, pp 173-184
Certain dietary components of plant origin may reduce the risk of prostate
cancer. A study consisted of 617 cases of prostate cancer and 636 disease
free individuals as controls from Ontario, Quebec, and British Columbia.
It found a decreasing, statistically significant association of prostate
cancer with increased consumption of green vegetables (-46%), tomatoes
(-36%), beans/lentils/nuts (-31%), and cruciferous vegetables (-31%).
Higher intakes of citrus and non-citrus fruit were also associated with
lower prostate cancer. Among the grains, refined-grain (white) bread
intake was associated with a decrease in risk (-35%). However, whole-grain
breakfast cereals were associated with a higher risk for prostate cancer.
Product of the Week
CALCIUM ASCORBATE POWDER
Calcium ascorbate is a pH neutralized Vitamin C powder. Each teaspoon
equals 3 grams calcium ascorbate. The powder is 10% calcium. Vitamin C
has many functions, among those being immune system enhancement, improved
wound healing, an antiatherosclerotic effect,strengthening of blood
vessels and capillaries, prevention and treatment of cancer and lowering
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