Geoff Smith wrote:
> ----------
> > From: Thom Quinn <thomquinn@esosoft.com>
> > To: extropians@extropy.com
> > Subject: junk DNA
> > Date: Monday, March 02, 1998 8:18 PM
> >
> > Hello, I am looking for a good review paper about the
> > various hypotheses on the possible functionality of
> > so-called junk DNA--the non-coding regions of eukaryotic
> > genomes. I am aware of some of the ideas (selfish DNA,
> > genome structural functions, etc.) but I would like to find
> > a review in the primary literature. Does such a thing exist?
>
> Selfish DNA, genome structural functions, and regulatory action(eg.
> heterochromatin and position-effect variegation) are all I can think of.
> Maybe you could check out some articles on transposons and/or
> heterochromatin. These articles are everywhere, and there are also many
> books on the subject. Here's a review paper on heterochromatin by a
> professor here at UBC:
>
> Grigliatti, T. A. 1991. "Position Effect Variegation- An Assay for
> Non-histone Chromosomal Proteins and Chromatin Assembly and Modifications
> Factors." Methods in Cell Biology 35: 587-627.
>
> > Thanks for you help!
> >
> > Thom Quinn
> > swo@execpc.com
> > quinn@evolutionary.org
> >
> >