fibers and lipase inhibition

From: Doug Skrecky (
Date: Mon Feb 12 2001 - 23:02:44 MST

[Fiber induced weight loss without the fiber?]

---------- Forwarded message ----------
  Various dietary fibers
  have different effects on lipase-catalyzed
  hydrolysis of tributyrin in vitro.
  Journal of Nutrition. 122(2):269-77, 1992 Feb.
  The ability of various dietary
  fibers to impede lipase-catalyzed hydrolysis of tributyrin
  was studied in vitro. Conditions (temperature, kind and concentration of
  constituents, pH, agitation) were chosen to mimic, as closely as possible,
  those prevailing in the human duodenum. Lipolysis was monitored at pH 6.0 and
  37 degrees C using a constant pH titrimeter. Some fibers
  inhibited lipolysis (red wheat bran, white wheat bran, oat bran and sugarbeet
  fiber), whereas most did not (psyllium seed, pectin LM 12CG, carrageenan,
  carboxymethylcellulose, gum arabic, and pectin slow set). Water extracts of
  the fibers accounted for 32-41% of the inhibitory effect of
  the two wheat brans on lipolysis and 100% of the inhibitory effect of oat

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