From: LEF Email List1 [mailto:nsantini@directnet1.net]
Sent: Thursday, March 16, 2000 12:35 PM
Subject: Life Extension Update 3-16-00
LEF Email List1 - http://www.lef.org
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The Life Extension Foundation has a 20 year history of introducing life
saving medical discoveries and funding scientific research.
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In This Issue 3-16-00: What's Hot!---FETAL NEURAL TRANSPLANTS OFFER HOPE
FOR PARKINSON'S, HEART PATIENTS DON'T TAKE ASPIRIN AS OFTEN AS
APPROPRIATE; Protocols--- INSOMNIA,
DOWN SYNDROME, EMPHYSEMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE,
FEMALE HORMONE MODULATION THERAPY, CHOLESTEROL REDUCTION, Products---
LIPAEN (CLA).
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FETAL NEURAL TRANSPLANTS OFFER HOPE FOR PARKINSON'S
Parkinson's disease causes stiffness, tremors, poor balance and other
neurological symptoms, partially due to a progressive loss of
dopamine-producing cells. Drugs to boost dopamine levels help but may
become less effective after five years. Pioneering research, reported in
the journal Neurology, shows embryonic dopamine-producing pig cell
implants have decreased symptoms in some patients.
http://www.lef.org/whatshot/index.html#pcto
HEART PATIENTS DON'T TAKE ASPIRIN AS OFTEN AS APPROPRIATE For
just a penny per day, patients with coronary artery disease could drop
their heart attack risk by one third. Yet nearly three quarters of
patients with a history of angina or heart attack do not take aspirin on a
regular basis. While aspirin use has increased, researchers at
Massachusetts General Hospital say more heart patients could benefit from
the inexpensive, effective drug.
http://www.lef.org/whatshot/index.html#hpdt
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INSOMNIA
Sleep is not a static condition but actually a fluid condition with
changes occurring through the sleep period. These stages demonstrate
different brain wave patterns. In particular, the period of so-called
rapid eye movement (REM) sleep is when we dream. There are about five
periods of REM during the night. The deepest periods of sleep, stages 3
and 4 occur earlier in the night. It is the deeper phases of sleep which
decrease in duration as we age.
To find the cause of insomnia one first attempts to find out whether it is
initiation maintenance of sleep that is the problem. One looks for the
more common insomnia precursors, such as stress related factors. An
increase in caffeine consumption includes not only tea and coffee, but
carbonated beverages as well. Shift workers often have a problem resetting
their biological clock to deal with a topsy turvy schedule. The use of
alcohol as a sedative before bed can have the opposite effect resulting in
further impaired sleep.
A common cause for insomnia in people over the age of 35 or 40 is
deficiency of the hormone melatonin. Melatonin is the hormone released by
the pineal gland that induces drowsiness, and enables the body to enter
the deep-sleep patterns characteristic of youth.
http://www.lef.org/protocols/prtcl-063.shtml
DOWN SYNDROME
Down syndrome (DS) is one of the most frequent congenital multiple
handicaps, occurring in 1 to 2 of every 1000 births. It is characterized
as a chromosomal disorder, resulting in mental retardation and physical
abnormalities. People born with DS have an extra chromosome, making three
of a kind, known as trisomy. Ninety-five percent of all DS cases are
caused from trisomy 21. People with this type of trisomy disorder
generally live until their 30s or 40s. Trisomy 21 (Down syndrome) is
characterized by delayed physical and mental development, with numerous
physical abnormalities. Trisomy 18 (Edwards syndrome) occurs in 1 of every
3000 births. It is characterized by severe mental retardation and facial
abnormalities. Other possible defects are cleft lip or palate, missing
thumbs, webbed hands, clubfeet, heart defects, and genitourinary defects.
Survival for more than a few months is rare. Trisomy 13 (Patau's syndrome)
occurs in 1 of every 5000 births. It is characterized by severe mental
retardation along with brain and eye defects. Other abnormalities may
include cleft lip or palate, heart and genitourinary defects, and
malformed ears. More than 80% of babies born with trisomy 13 do not
survive past the age of 1 year.
Children with DS who were supplemented for the first three years of life
with a combination of vitamin B6 and 5-hydroxytryptophan improved in
social maturity and accomplishment.
http://www.lef.org/protocols/prtcl-045.shtml
EMPHYSEMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE
There are several lung diseases collectively known as Chronic Obstructive
Pulmonary Disease (COPD), including asthmatic bronchitis, chronic
bronchitis (with normal airflow), chronic obstructive bronchitis, bullous
disease, and emphysema. About 11% of the population of the United States
suffers from COPD, with the disease becoming increasingly common among
older women. According to the Mayo Clinic, COPD kills 85,000 people a year
in the United States.
The incidence of emphysema, the fourth leading cause of death in the
United States, is up more than 40% since 1982. Emphysema ranks fifteenth
among chronic diseases that contribute to limitation of physical activity.
About 44% of those with emphysema report that their daily activities have
been limited by the condition. According to the National Jewish Medical
and Research Center in Denver, this chronic lung disease kills 13,000
people a year in the United States alone, but up to 2.4 million Americans
are estimated to be suffering from this debilitating condition. Emphysema
permanently enlarges and irreversibly damages the alveoli, damages the
ends and walls of the smallest bronchioles (the tiny breathing tubes that
branch off from the trachea and bronchi), and diminishes the elasticity of
the lung.
http://www.lef.org/protocols/prtcl-046.shtml
FEMALE HORMONE MODULATION THERAPY
Concern about the life-threatening side effects of synthetic hormone drugs
has caused many women to be deprived of the benefits of safe, natural
hormone replacement therapy.
Proper hormone modulation can prevent degenerative disease and improve
functioning in both the physical and emotional spheres of life, both at
menopause and throughout life. For example, many sexual "dysfunctions,"
including lack of desire can be mitigated when hormone levels are
naturally restored to a youthful profile. Menopause might also be delayed
and less traumatic if hormone adjustments are made in time. Numerous
female health problems are tied to inadequate hormone balances, as we will
show.
Forty-five million women are menopausal in the United States today;
another 3.5 million women will become menopausal this year. Based on life
expectancy trends, women face the prospect of spending the last one-third
to one-half of their lives in a state of hormonal imbalance. The quality
and quantity of life for these women will be determined by how well they
(and their doctors) manage their hormone replacement.
http://www.lef.org/protocols/prtcl-133.shtml
CHOLESTEROL REDUCTION
Elevated cholesterol is associated with a greater than normal risk of
atherosclerosis and cardiovascular disease. While antioxidants can inhibit
cholesterol from oxidizing onto the linings of the arteries, knowing and
controlling your cholesterol levels is still an important step in
preventing cardiovascular disease.
Low Density Lipoprotein (LDL) is called the "bad" form of cholesterol. LDL
carries most of the cholesterol in the blood, and the cholesterol from
LDLs is the main source of damaging accumulation and blockage in the
arteries.
High Density Lipoprotein (HDL) is called the "good" form of cholesterol.
HDL picks up and transports cholesterol in the blood back to the liver,
which leads to its elimination from the body.
The following factors appear to have the greatest impact on cholesterol
levels: heredity, diet, weight, age, sex, alcohol and stress.
Curcumin , also known as turmeric root, an ancient spice in the ginger
family, is gaining attention for its positive impact on a number of
diseases, including cholesterol reduction. Scientific evidence has been
building since the mid 1980s of curcumin's potential cholesterol lowering
capabilities.
http://www.lef.org/protocols/prtcl-032.shtml
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LIPAEN (CLA)
Conjugated linoleic acid (CLA) is a potent antioxidant, anti- carcinogen,
and anti-catabolite, as well as a powerful immune system enhancer. The
effect of CLA in preventing cancer is very specific. CLA is more powerful
than any other fatty acid in modulating tumor development. CLA reduces or
stops the negative effects of catabolism.
CLA is the component of red meat that has been shown to prevent cancer.
The FDA has published research attesting to the anti-cancer properties of
CLA. CLA is used by body builders to drive glucose into muscle cells to
produce anabolic effects. Dieters use this same sugar burning mechanism to
prevent serum glucose from turning into body fat. The new CLA oil is about
50% stronger in the cis-9, trans- 11, isomer (which scientists consider
the most active isomer).
The CLA fraction is over 70% in the new CLA compared to 60% in the
previous version. CLA is listed under the ESSENTIAL FATTY ACIDS section.
www.lef.org/newshop/items/item00289.html
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Please visit our web site at www.lef.org.
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Sincerely,
Nicki Santini
E-mail Update Editor
Nicki@lef.org
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See You Next Week!
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